During the audit of Searle’s DKP study,  pathologist Dr. Charles H. Frith spent three days with the FDA task force to review 145 animals.  Sufficient slides substantiated 73 female animals with grossly observed masses. 

THREE ASPARTAME FEMALES WITH TUMORS

In 2005, Dr. Morando Soffritti of the European Foundation of Oncology, in Bologna, Italy completed an 8-year “mega-experiment” with1800 rats, to evaluate the potential carcinogenic effects of aspartame. 

The results of the experiment showed a dose-related statistically significant increase of lymphomas and leukemias in female rats.  This statistically significant increase was also observed at the dose level of 20 mg/Kg of body weight, a dose inferior to the accepted daily intake permitted by current regulations.

Results of Dr. Soffritti’s second long-term carcinogenicity bioassay on Aspartame  …”not only confirm but also reinforce our first experimental demonstration (Belpoggi et al. 2006; Soffritti et al. 2005, 2006) of APM's multipotential carcinogenicity at a dose level close to the human ADI.  Furthermore, the study demonstrates that when life-span exposure to APM (aspartame) begins during fetal life, its carcinogenic effects are increased.”

I was relieved to know to know Dr. Soffritti also let his rats live until spontaneous death because most cancers occur  “in the last third of a person’s lifetime.”

There are no photographs from the Soffritti study.  But one can surmise, they looked something like this.

THESE FEMALES IN MY MINI-EXPERIMENT APPEAR TO HAVE MAMMARY OR LYMPH TUMORS.

THIS FEMALE DEVELOPED A LARGE TUMOR ON HER LEFT SIDE.

THIS FEMALE DEVELOPED A TUMOR ON THE RIGHT SIDE OF HER FACE.  

THIS FEMALE HAS A VERY LARGE TUMOR ON HER RIGHT SIDE.  

THIS MALE HAD A GROWTH ON THE RIGHT SIDE OF HIS FACE.